PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis Three alternatively spliced transcript variants

Three alternatively spliced transcript variants that encode different protein isoforms have been described

and thus may transduce signals for cell survival and proliferation

NECTIN1 encodes nectin cell adhesion molecule 1 that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells

Does not affect the proliferation of cancer cells in vitro

Mutations in this gene are associated with the congenital disorder of glycosylation type IIe

PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis Three alternatively spliced transcript variantsPresenilins which are components of the gamma secretase protein complex are required for intramembranous processing of some type I transmembrane proteins such as the Notch proteins and the beta amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta amyloid precursor protein generates neurotoxic amyloid beta peptides the major component of senile plaques associated with