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APLP-1 Polyclonal Antibody, 100ul Thermal Control It is a C-type lectin

SKU: 64848674863

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APLP-1 Polyclonal Antibody, 100ul Thermal Control It is a C-type lectinAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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Description

It is a C-type lectin with mannose binding specificity

An important paralog of this gene is HAP1

Alternatively spliced transcript variants encoding multiple isoforms have been observed for SLC9A3R2

Although there is no evidence of transcription from this pseudogene

In migrating cells

APLP-1 Polyclonal Antibody, 100ul Thermal Control It is a C-type lectinAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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