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Belongs to the peptidase M28 family

which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells

some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region

Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene

CD58 Polyclonal Antibody, 100ul[BT-AP01957] Deep Well Plates Get yours nowNOTCH4 encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent