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p47-phox Polyclonal Antibody, 50ul[BT-AP06791] Molecular Sciences Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment

SKU: 65138996609

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p47-phox Polyclonal Antibody, 50ul[BT-AP06791] Molecular Sciences Posttranslational glycosylphosphatidylinositol (GPI) anchor attachmentThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.

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Description

Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane

This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins

This gene is one of a cluster of highly related genes located at chromosomal region 19q13

elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor

Alpers-Huttenlocher syndrome (AHS)

p47-phox Polyclonal Antibody, 50ul[BT-AP06791] Molecular Sciences Posttranslational glycosylphosphatidylinositol (GPI) anchor attachmentThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.

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