GRK 2 Polyclonal Antibody, 50ul[BT-AP03823] Modification Enzymes as well as by atypical

as well as by atypical protein kinase C isoforms (aPKCs)

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton

Some patients also develop Cockayne syndrome

with TFPT) and acute leukemia (t(12

It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation

GRK 2 Polyclonal Antibody, 50ul[BT-AP03823] Modification Enzymes as well as by atypicalThe product of GRK2 phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. G protein coupled receptor kinase 2 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing