TRPV5 Polyclonal Antibody, 100ul Buffer Solutions Oncogenic fusions of the 5'

Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias

Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified

There is a pseudogene of this gene on chromosome 17

Interacts with NCOA3 and NCOA6 coactivators| leading to a strong increase of transcription of target genes

and is expressed specifically in the testis

TRPV5 Polyclonal Antibody, 100ul Buffer Solutions Oncogenic fusions of the 5'This gene is a member of the transient receptor family and the TrpV subfamily. The calcium selective channel encoded by this gene has 6 transmembrane spanning domains, multiple potential phosphorylation sites, an N linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.