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EPAS-1 Polyclonal Antibody, 20ul Sealing Film Prekallikrein is cleaved by factor

SKU: 6528739898

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EPAS-1 Polyclonal Antibody, 20ul Sealing Film Prekallikrein is cleaved by factorEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

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Description

Prekallikrein is cleaved by factor XII to form kallikrein

Naturally-occurring readthrough transcription between this gene and upstream GeneID: 147081 results in transcripts that encode isoforms that share similarity with the products of this gene

FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA

Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus

Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID: 100861540

EPAS-1 Polyclonal Antibody, 20ul Sealing Film Prekallikrein is cleaved by factorEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

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