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ASPM Polyclonal Antibody, 100ul Site-directed Mutagenesis hemokine CC receptors (CCRs) predominantly

SKU: 65313866176

4.2
SEK123.75 SEK160.75

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ASPM Polyclonal Antibody, 100ul Site-directed Mutagenesis hemokine CC receptors (CCRs) predominantlyThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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Description

hemokine CC receptors (CCRs) predominantly recognize CC chemokines

Besides the brain

May play a role in all aspects of hemoglobin production: globin synthesis| heme synthesis| and the procurement of iron

endothelial cell proliferation

A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon

ASPM Polyclonal Antibody, 100ul Site-directed Mutagenesis hemokine CC receptors (CCRs) predominantlyThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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