CEP55(Phospho Ser425) Polyclonal Antibody, 100ul Microplate Mixer Casein kinase I family members

Casein kinase I family members

High tensile strength

The product of this gene belongs to the Serine/Threonine protein kinase family| and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation

As such it functions as a negative regulator of many signal transduction pathways

CEP55(Phospho Ser425) Polyclonal Antibody, 100ul Microplate Mixer Casein kinase I family membersPlays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.,PTM: There is a hierachy of phosphorylation, where both Ser 425 and Ser 428 are phosphorylated at the onset of mitosis, prior to Ser 436. Phosphorylation at Ser 425 and Ser 428 is required for dissociation from the centrosome at the G2 M boundary. Phosphorylation at the 3 sites, Ser 425, Ser 428 and Ser 436,