CD63 Polyclonal Antibody, 100ul[BT-AP01878] Culture Media with this abnormal accumulation being

with this abnormal accumulation being specific to alpha-synucleinopathy lesions

Strongly expressed after meiosis

autosomal dominant or X-linked inheritance

Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis

located in the cytoplasm

CD63 Polyclonal Antibody, 100ul[BT-AP01878] Culture Media with this abnormal accumulation beingACAN is a member of the aggrecan versican proteoglycan family. Aggrecan core protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.