Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression This protein may function in

This protein may function in vesicle trafficking| membrane fusion| protein complex assembly and cell motility

suggesting that this kinase may serve as an intermediate in the response to cellular stress

which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB

and peripheral blood leukocytes

Following activation

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression This protein may function inMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.