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ZEB1 Polyclonal Antibody, 100ul Bottles This gene encodes a member

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ZEB1 Polyclonal Antibody, 100ul Bottles This gene encodes a memberThis gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy 3 and late onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.

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Description

This gene encodes a member of the granzyme subfamily of proteins

Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network

Transcription cofactor HES-6 encoded by HES6 functions as a cofactor

Modulates the placental expression of CYP11A1

The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells

ZEB1 Polyclonal Antibody, 100ul Bottles This gene encodes a memberThis gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy 3 and late onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.

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