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HER4/ErbB4(Phospho-Tyr984) Rabbit Polyclonal Antibody, 20ul Aspirating Pipets KCNT1 (potassium sodium-activated channel subfamily

SKU: 66135666082

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HER4/ErbB4(Phospho-Tyr984) Rabbit Polyclonal Antibody, 20ul Aspirating Pipets KCNT1 (potassium sodium-activated channel subfamilyThis gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single pass type I membrane protein with multiple cysteine rich domains a transmembrane domain a tyrosine kinase domain a phosphotidylinositol 3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis

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Description

KCNT1 (potassium sodium-activated channel subfamily T member 1) encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways

This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes

Downregulation of this gene may play a role in type 2 diabetes

The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells

Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20

HER4/ErbB4(Phospho-Tyr984) Rabbit Polyclonal Antibody, 20ul Aspirating Pipets KCNT1 (potassium sodium-activated channel subfamilyThis gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single pass type I membrane protein with multiple cysteine rich domains a transmembrane domain a tyrosine kinase domain a phosphotidylinositol 3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis

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