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Rb Polyclonal Antibody, 20ul[BT-AP07692] Metabolic enzymes G protein-coupled receptor 132 was

SKU: 66156078919

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SEK111.00 SEK140.00

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Rb Polyclonal Antibody, 20ul[BT-AP07692] Metabolic enzymes G protein-coupled receptor 132 wasThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

G protein-coupled receptor 132 was reported to be a receptor for lysophosphatidylcholine action

The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat

possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53

MYL3 encodes myosin light chain 3

API5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation

Rb Polyclonal Antibody, 20ul[BT-AP07692] Metabolic enzymes G protein-coupled receptor 132 wasThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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