CENPC Polyclonal Antibody, 20ul Cryopreservation The protein encoded by this

The protein encoded by this gene is similar to the protein transgelin| which is one of the earliest markers of differentiated smooth muscle

May be involved in neuronal NGF-dependent Ca(2+) influx

which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation

Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients

and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase

CENPC Polyclonal Antibody, 20ul Cryopreservation The protein encoded by thisCentromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.