ZBTB45 Polyclonal Antibody, 20ul Thermal Control Mutations causing Bloom syndrome delete

Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity

It is not active until the last four amino acids of the carboxy-terminus have been cleaved off

They alter the interaction of IGFs with their cell surface receptors

and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types

consistent with the observation that it binds directly to pre-mRNA

ZBTB45 Polyclonal Antibody, 20ul Thermal Control Mutations causing Bloom syndrome deleteMay be involved in transcriptional regulation.,Belongs to the krueppel C2H2 type zinc finger protein family.,Contains 1 BTB (POZ) domain.,Contains 4 C2H2 type zinc fingers.,