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IGF-IR(Phospho Tyr1346) Polyclonal Antibody, 50ul Culture Tubes with high expression seen in

SKU: 66236874494

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IGF-IR(Phospho Tyr1346) Polyclonal Antibody, 50ul Culture Tubes with high expression seen inThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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Description

with high expression seen in adult muscle

with widened bottom edge and good stability on table surface

mutations in this gene are thought to confer a predisposition to sarcomas

neuromedin N and neurotensin

There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites

IGF-IR(Phospho Tyr1346) Polyclonal Antibody, 50ul Culture Tubes with high expression seen inThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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