BRCA2 Polyclonal Antibody, 100ul Antibodies Studies of the mouse and

Studies of the mouse and chick homologs revealed roles in midbrain and limb development

subunit:Interacts with RIMS1 and RIMS2

The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2)

UBE2D2 encodes a member of the E2 enzyme family

and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B

BRCA2 Polyclonal Antibody, 100ul Antibodies Studies of the mouse andInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is