OAZ2 Polyclonal Antibody, 20ul Cell Dissociation Multiple transcript variants generated by

Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported| but the full-length nature and biological validity of some variants have not been defined

Mutations in IKBKG result in incontinentia pigmenti

but their full length sequences have not been determined

The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding

Necessary for scanning and involved in initiation site selection

OAZ2 Polyclonal Antibody, 20ul Cell Dissociation Multiple transcript variants generated byThe protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This