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DNA-PKCS Polyclonal Antibody, 20ul[BT-AP02678] Protein Modification An allelic polymorphism in this

SKU: 6636674101

4.2
PLN97.20 PLN122.20

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DNA-PKCS Polyclonal Antibody, 20ul[BT-AP02678] Protein Modification An allelic polymorphism in thisPRKDC encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein (protein kinase, DNA activated, catalytic polypeptide) encoded is a member of the PI3 PI4 kinase family.

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Description

An allelic polymorphism in this gene results in both coding and non-coding variants

Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression

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It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis

The encoded protein (caspase recruitment domain family member 6) is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB

DNA-PKCS Polyclonal Antibody, 20ul[BT-AP02678] Protein Modification An allelic polymorphism in thisPRKDC encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein (protein kinase, DNA activated, catalytic polypeptide) encoded is a member of the PI3 PI4 kinase family.

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