Rat Glypican-3, GPC-3 ELISA Kit, 96T Electronic Pipette mediation of synaptic function and

mediation of synaptic function and cell survival after ischemia

Alternative splicing results in multiple transcript variants encoding distinct isoforms

This gene is widely expressed in many tissues with the greatest abundance in brain and testis

tumor invasion

May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity

Rat Glypican-3, GPC-3 ELISA Kit, 96T Electronic Pipette mediation of synaptic function andCell surface proteoglycan that bears heparan sulfate (By similarity). Negatively regulates the hedgehog signaling pathway when attached via the GPI anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (By similarity). Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation (By similarity). Positively regulates the canonical