Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis which further interacts with the

which further interacts with the other family members

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

and susceptibility to Legionnaire disease

Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis which further interacts with theVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.