Jagged1 Polyclonal Antibody, 50ul[BT-AP04681] Bacterial Expression lung or pancreas

lung or pancreas

It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis

Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes

corneal epithelium

which are composed of this protein

Jagged1 Polyclonal Antibody, 50ul[BT-AP04681] Bacterial Expression lung or pancreasThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.