Atm Polyclonal Antibody, 100ul[BT-AP00724] Multi-Layer Cell Culture System Deficiency of this enzyme results

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

Appears to mediate neuronal differentiation

Compatible with a wide range of micropipettes

The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain

Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly

Atm Polyclonal Antibody, 100ul[BT-AP00724] Multi-Layer Cell Culture System Deficiency of this enzyme resultsThe protein encoded by ATM belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell