Stat3 Polyclonal Antibody, 20ul[BT-AP14539] Drying & Desiccation and is overexpressed in the

and is overexpressed in the tumors of various epithelial cancers

The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and| when overexpressed| induces apoptosis

possibly via its association with CK2 and PKD kinases

stabilizes the FRAP1-RAPTOR interaction and favors RAPTOR-mediated inhibition of FRAP1 activity

it is not incorporated into COPII carriers and remains in the endoplasmic reticulum membrane

Stat3 Polyclonal Antibody, 20ul[BT-AP14539] Drying & Desiccation and is overexpressed in theThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and