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VPS35 Polyclonal Antibody, 100ul Isothermal Amplification This protein may play an

SKU: 6719030659

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VPS35 Polyclonal Antibody, 100ul Isothermal Amplification This protein may play anVPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and

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Description

This protein may play an important role in both nuclear and mitochondrial base excision repair

The other predicted transmembrane region is probably a hairpin-type region embedded into the membrane

where it functions as a negative regulator of cell growth and survival

Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect

such as Skp2

VPS35 Polyclonal Antibody, 100ul Isothermal Amplification This protein may play anVPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and

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