GLI-3 Polyclonal Antibody, 100ul Microplate Mixer some seem to shuttle between

some seem to shuttle between the nucleus and the cytoplasm

May act as a calcium-activated chloride channel

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes

serine/threonine kinase) is the cellular homolog of viral raf gene (v-raf)

This protein mediates the expression of a variety of genes| which is thought to be important for cell viability in response to different cell stimuli and pathogens

GLI-3 Polyclonal Antibody, 100ul Microplate Mixer some seem to shuttle betweenGLI3 encodes GLI family zinc finger 3 which belongs to the C2H2 type zinc finger proteins subclass of the Gli family. They are characterized as DNA binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated