FADD Polyclonal Antibody, 100ul[BT-AP03128] Bio-Reaction Tube This protein is a receptor

This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight)

Alternative splicing of this gene results in several transcript variants

May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways

The gene encompasses the common fragile site FRA3B on chromosome 3

Contains 1 RINT1/TIP20 domain

FADD Polyclonal Antibody, 100ul[BT-AP03128] Bio-Reaction Tube This protein is a receptorThe protein encoded by FADD (Fas associated via death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C terminal death domain, this protein can be recruited by TNFRSF6 Fas receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10 TRAIL receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the