S5A2 Polyclonal Antibody, 100ul Antibody Humanization Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants

Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia

leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD

miscellaneous:'Reprimo' signifies stop/repress

This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B)

S5A2 Polyclonal Antibody, 100ul Antibody Humanization Alternative splicing of this geneThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).