Human Integrin Alpha-3, ITGA3 ELISA Kit, 96T Serum The encoded protein contains two

The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain

Mutations in this gene are implicated in bleeding disorder

Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis

The protein encoded by this gene plays important roles in the determination of centrosome position and segregation

PubMed: 22473704)

Human Integrin Alpha-3, ITGA3 ELISA Kit, 96T Serum The encoded protein contains twoIntegrin alpha 3 beta 1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha 3 beta 1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha 3 beta 1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells