PERK Monoclonal Antibody, 100ul In vitro Assessment The ARF genes encode small

The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D

The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis

It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions

A pseudogene has been identified on chromosome 3q29

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily

PERK Monoclonal Antibody, 100ul In vitro Assessment The ARF genes encode smallThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in