Nibrin Polyclonal Antibody, 50ul[BT-AP06022] Immune Cell Analysis The protein encoded by this

The protein encoded by this gene represents the alpha subunit

the attachment rate of cells surpasses 90%

|Contains 1 PA (protease associated) domain

Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity)

The encoded protein contains several KH domains

Nibrin Polyclonal Antibody, 50ul[BT-AP06022] Immune Cell Analysis The protein encoded by thisMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.