SH3B4 Polyclonal Antibody, 20ul Immunoassays Mutations in TSC2 lead to

Mutations in TSC2 lead to tuberous sclerosis complex

SOX17 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate

X-linked encoded by DDX3X is a member of the large DEAD-box protein family

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors

8) is a DNA binding protein

SH3B4 Polyclonal Antibody, 20ul Immunoassays Mutations in TSC2 lead toThis gene encodes a protein with 3 Asn Pro Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo specific control of clathrin mediated endocytosis, specifically controlling the internalization of a specific protein receptor.