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STXB2 Rabbit Polyclonal Antibody, 50ul Stepper This protein was first identified

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STXB2 Rabbit Polyclonal Antibody, 50ul Stepper This protein was first identifiedThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells| however

CLDN2 (claudin 2) product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions

GPR35 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell

Activates RAC1

Pseudogenes are present on chromosomes 5 and 22

STXB2 Rabbit Polyclonal Antibody, 50ul Stepper This protein was first identifiedThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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