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TdT Polyclonal Antibody, 100ul Diagnostic Probes & Oligos POLR2E (RNA polymerase II subunit

SKU: 67932120867

4.3
USD108.00 USD136.00

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TdT Polyclonal Antibody, 100ul Diagnostic Probes & Oligos POLR2E (RNA polymerase II subunitDNTT is a member of the DNA polymerase type X family and encodes a template independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre B and pre T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non germ line elements (N regions)

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Description

POLR2E (RNA polymerase II subunit E) encodes the fifth largest subunit of RNA polymerase II

This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues

AMPA receptors mediate fast synaptic neurotransmission in the central nervous system

Vesicle transport through interaction with t-SNAREs homolog 1A encoded by VTI1A is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking

Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes

TdT Polyclonal Antibody, 100ul Diagnostic Probes & Oligos POLR2E (RNA polymerase II subunitDNTT is a member of the DNA polymerase type X family and encodes a template independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre B and pre T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non germ line elements (N regions)

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