DMRT2 Rabbit Polyclonal Antibody, 20ul Microplate Mixer The nuclear pore complex (NPC)

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macro

The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity

GO annotations related to this gene include hydrolase activity and palmitoyl-CoA hydrolase activity

Its expression is restricted to premeiotic germ cells| particularly in spermatogonia

DMRT2 Rabbit Polyclonal Antibody, 20ul Microplate Mixer The nuclear pore complex (NPC)The protein encoded by this gene belongs to the DMRT gene family sharing a DM DNA binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 genes involved in sex determination in these organisms. Also this gene is located in a region of the human genome (chromosome 9p24. 3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex determining gene(s) on chr 9.