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ET-1 Polyclonal Antibody, 100ul Cell Biology IL4I1 encodes interleukin 4 induced

SKU: 6815668591

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ET-1 Polyclonal Antibody, 100ul Cell Biology IL4I1 encodes interleukin 4 inducedEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

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Description

IL4I1 encodes interleukin 4 induced 1 with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor

The protein encoded by VAMP4 (vesicle associated membrane protein 4) is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family

Class-5 subfamily

2 (PRYSPRY) domain

The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity

ET-1 Polyclonal Antibody, 100ul Cell Biology IL4I1 encodes interleukin 4 inducedEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

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