AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation TP53 encodes a tumor suppressor

TP53 encodes a tumor suppressor protein containing transcriptional activation

Diseases associated with C2orf40 include esophageal cancer

Mutations in this gene are associated with several congenital cardiovascular malformations

fetal and neonatal tissues

Contains 1 MAGE domain

AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation TP53 encodes a tumor suppressorThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).