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c-Fos Monoclonal Antibody(6A3), 50ul Lentiviral Packaging Component of the NF-kappa-B p52-c-Rel

SKU: 68304550046

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c-Fos Monoclonal Antibody(6A3), 50ul Lentiviral Packaging Component of the NF-kappa-B p52-c-RelThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

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Description

Component of the NF-kappa-B p52-c-Rel complex

It may be involved in cellular excitability of restricted neurons in the central nervous system

It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A

Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats| and an intracellular domain consisting of multiple different domain types

he inward-rectifier potassium channel family (also known as 2-TM channels) include the strong inward-rectifier channels (Kir2

c-Fos Monoclonal Antibody(6A3), 50ul Lentiviral Packaging Component of the NF-kappa-B p52-c-RelThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

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