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Rabbit Endothelin 1, ET-1 ELISA Kit, 96T Capsule Filter Pan3 exists as three isoforms

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Rabbit Endothelin 1, ET-1 ELISA Kit, 96T Capsule Filter Pan3 exists as three isoformsEndothelins are endothelium derived vasoconstrictor Peptides (By similarity). Probable ligand for G protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity).

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Description

Pan3 exists as three isoforms produced by alternative splicing and the gene encoding Pan3 is located on human chromosome 13

a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta)

This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones

these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate

Involved in cardiac development

Rabbit Endothelin 1, ET-1 ELISA Kit, 96T Capsule Filter Pan3 exists as three isoformsEndothelins are endothelium derived vasoconstrictor Peptides (By similarity). Probable ligand for G protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity).

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