TFPI Polyclonal Antibody, 100ul Pipette Micro Tips Mutations in this gene have

Mutations in this gene have been associated with the Proteus syndrome

Like other cytokine receptors

PMID: 15805470)

VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm

Three transcript variants encoding two different isoforms have been found for POLR2E

TFPI Polyclonal Antibody, 100ul Pipette Micro Tips Mutations in this gene haveTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.