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Rat Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit, 96T Petri Dishes PubMed: 27293190)

Rat Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit, 96T Petri Dishes PubMed: 27293190)

Name: Rat Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit, 96T Petri Dishes PubMed: 27293190)
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SKU: 69031593409
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SKU: 69031593409

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Rat Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit, 96T Petri Dishes PubMed: 27293190)Antagonist of signaling by TGF beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF beta receptor complex. Also acts by recruiting the PPP1R15A PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1

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Description

PubMed: 27293190)

Potential oncogene (By similarity)

The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis

effectively detoxifying these molecules

A translocation

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