GADD 45 Gamma Polyclonal Antibody, 50ul Plasma Mutations in this gene cause

Mutations in this gene cause Griscelli syndrome type-1 (GS1)

TYMP encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells

It is comprised of subunits linked by interchain disulfide bonds to form large| variably sized homomultimers

The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins

which is found in the large histone gene cluster on chromosome 6p22-p21

GADD 45 Gamma Polyclonal Antibody, 50ul Plasma Mutations in this gene causeGADD45G is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA damaging agents. Growth arrest and DNA damage inducible protein GADD45 gamma encoded by GADD45G responds to environmental stresses by mediating activation of the p38 JNK pathway via MTK1 MEKK4 kinase. The GADD45G is highly expressed in placenta.