LRRK2 Polyclonal Antibody, 50ul Miscellaneous Keratin 18

Keratin 18

In the developing cortex| cortical neurons must migrate over long distances to reach the site of their final differentiation

It forms a unique glycan

some of which may result in the formation of fusion proteins

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

LRRK2 Polyclonal Antibody, 50ul Miscellaneous Keratin 18This gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.