Dysferlin Polyclonal Antibody, 20ul Capsule Filter The primary defect in NCL

The primary defect in NCL disorders is thought to be associated with lysosomal storage function

It is also involved in other processes including cell migration and adhesion

with a recovery rate over 90%

Alternatively spliced transcript variants of this gene have been reported

ARMCX3 (armadillo repeat containing

Dysferlin Polyclonal Antibody, 20ul Capsule Filter The primary defect in NCLThe protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by DYSF binds caveolin 3, a skeletal muscle membrane protein which is important in the