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WDR85 Rabbit Polyclonal Antibody, 20ul RNA Synthesis Consortin (CNST) is an integral

SKU: 69468312620

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WDR85 Rabbit Polyclonal Antibody, 20ul RNA Synthesis Consortin (CNST) is an integralDiphthamide is a post translationally modified histidine residue present in elongation factor 2 and is the target of diphtheria toxin. This gene encodes a protein that contains a WD 40 domain and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase converting methylated diphthine to diphthine which can then undergo amidation to produce diphthamide.

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Description

Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins| the building blocks of gap junctions| and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al

The signal transduction of this receptor is mediated by various death domain containing adaptor proteins

and may be related to tumor metastasis

|PTM:The level of phosphorylation appears to be regulated during the cell cycle

With 10 layers of reload packing

WDR85 Rabbit Polyclonal Antibody, 20ul RNA Synthesis Consortin (CNST) is an integralDiphthamide is a post translationally modified histidine residue present in elongation factor 2 and is the target of diphtheria toxin. This gene encodes a protein that contains a WD 40 domain and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase converting methylated diphthine to diphthine which can then undergo amidation to produce diphthamide.

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