RECK Polyclonal Antibody, 20ul Reagent Reservoirs Eight alternatively spliced transcript variants

Eight alternatively spliced transcript variants have been described

processing and nuclear export

Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N

or GRIN2D) and NR3 (GRIN3A or GRIN3B)

This gene is located in a cluster on chromosome 10 with five other closely related genes

RECK Polyclonal Antibody, 20ul Reagent Reservoirs Eight alternatively spliced transcript variantsThe protein encoded by RECK (reversion inducing cysteine rich protein with kazal motifs) is a cysteine rich, extracellular protein with protease inhibitor like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase 9, a key enzyme involved in tumor invasion and metastasis.