MRP-L24 Polyclonal Antibody, 100ul Cell Separation and Collection is due to mutations in

is due to mutations in the ALMS1 gene

Mutations in this gene cause atrial septal defect with atrioventricular conduction defect

Found in a pre-mRNA exonic splicing enhancer (ESE) complex with SNRP70

This interaction is inversely correlated to the length of the polyglutamine tract added to the huntingtin protein in Huntington disease

This attachment promotes terminal maturation and enucleation of erythroblasts

MRP-L24 Polyclonal Antibody, 100ul Cell Separation and Collection is due to mutations inMammalian mitochondrial ribosomal protein L 24 (39S ribosomal protein L24 mitochondrial) is encoded by nuclear gene MRPL24 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and