BIRC2 Polyclonal Antibody, 50ul Oligo Pool C-Jun-amino-terminal kinase-interacting protein 3 encoded

C-Jun-amino-terminal kinase-interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene

This gene encodes an epsilon subunit

Forms a ternary complex with TRIM63 and PRKCE

This protein is a tether

The gene is found in the large histone gene cluster on chromosome 6| near the major histocompatibility complex (MHC) class I region

BIRC2 Polyclonal Antibody, 50ul Oligo Pool C-Jun-amino-terminal kinase-interacting protein 3 encodedThe protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.