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CD58 Polyclonal Antibody, 100ul[BT-AP02462] Centrifugal Filter PGA5 is found in a

SKU: 69946379077

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CD58 Polyclonal Antibody, 100ul[BT-AP02462] Centrifugal Filter PGA5 is found in aKRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12 p11.

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Description

PGA5 is found in a cluster of related genes on chromosome 11

which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix

Interacts with FCGR1A

CCR4-NOT transcription complex subunit 7 encoded by CNOT7 binds to an anti-proliferative protein

This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex

CD58 Polyclonal Antibody, 100ul[BT-AP02462] Centrifugal Filter PGA5 is found in aKRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12 p11.

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